Coordination Compounds of Hexamethylenetetramine with Metal Salts: A Review

Photochemistry of Transition Metal Coordination Compounds

TIlE BACTERICIDAL PROPERTIES OF THE QUATERNARY SALTS OF HEXAMETHYLENETETRAMINE

The researches of Ehrlich and his coworkers during the past decade, which led to the discovery of salvarsan, have created a new procedure in the search for remedies for the control of infectious diseases. The discovery of this drug was the result of a logically conducted development of the chemistry of organic arsenic compounds in the directions indicated by their biological properties. This ne...

The Bactericidal Properties of the Quaternary Salts of Hexamethylenetetramine

The extension of the study of the quaternary salts of hexamethylenetetramine to those obtained by the addition of this base to the most varied types of substances containing aliphatically bound halogen has demonstrated that the introduction of the hexamethylenetetramine nucleus in this manner results in the production of bactericidal substances or enhances the bactericidal action if already pre...

Evaluation of the metal-dependent cytotoxic behaviour of coordination compounds.

The [Cu(L)Cl2]2 and [Pt(L)Cl2] complexes were prepared from the simple Schiff-base ligand (E)-phenyl-N-((pyridin-2-yl)methylene)methanamine (L) and respectively, CuCl2 and cis-[PtCl2(DMSO)2]. DNA-interaction studies revealed that the copper complex most likely acts as a DNA cleaver whereas the platinum complex binds to the double helix. Remarkably, cell-viability experiments with HeLa, MCF7 and...

CrystalExplorer model energies and energy frameworks: extension to metal coordination compounds, organic salts, solvates and open-shell systems

The application domain of accurate and efficient CE-B3LYP and CE-HF model energies for intermolecular interactions in molecular crystals is extended by calibration against density functional results for 1794 molecule/ion pairs extracted from 171 crystal structures. The mean absolute deviation of CE-B3LYP model energies from DFT values is a modest 2.4 kJ mol-1 for pairwise energies that span a r...